Projects

Here you can find a list of projects, which are financially supported by Reliable Cancer Therapies.

Adoptive T cell transfer and vaccination as treatment for stage IV melanoma in patients

The activation and expansion of tumor reactive T cells outside a patients body and their subsequent re-infusion (adoptive cell transfer (ACT)) is at this moment the most effective approach to induce objective anti-tumor responses in end-stage metastasized melanoma patients.

Verelst Uterine Cancer Fund

Pre-clinical evaluation of available targeted therapies and development of immunotherapy for endometrial cancer.

Artemisia annua (Sweet Wormwood)

RCT is funding a project where a specific extract of Artemisia annua will be evaluated as an anti-cancer therapy.

The role of the vagus nerve in cancer prognosis

This research aims to extend the investigation of the role of vagal activity in cancer prognosis and to test the hypothesized underlying mechanisms in clinical trials.

Synchronization of chemotherapy to the anti-tumor immune cycle

In this clinical trial, funded by RCT and performed in Melbourne (Australia) and Leuven (Belgium), patients with ovarian or endometrial carcinoma will undergo frequent blood drawings over a 2 week period to identify the immune cycle followed by oral low dose cyclophosphamide treatment at certain stages of the immune cycle.

Sodium bicarbonate

A pilot study which investigates if oral bicarbonate as an adjuvant can reduce pain in patients with tumor related pain. Furthermore, a phase 1 study of oral sodium bicarbonate is performed in patients with unresectable pancreatic carcinoma treated with gemcitabine.

Dichloroacetate (DCA)

Phase 1, Open-Label, Single-Arm, Clinical and Metabolomic Study of Dichloroacetate (DCA) in Adults with Recurrent Malignant Brain Tumors

EFFECT- EFFectiveness of Endometrial Cancer Treatments

EFFECT is a project aiming to compare the effectiveness of the different therapeutic strategies in the management of endometrial cancer in Belgium.

The use of standardized plant extracts for the treatment of cancer

Analysis and standardization of several plant extracts followed by pre-clinical evaluation of anti-cancer efficacy.

An HPLC-based assay for cytochrome P450 CYP1A1 and CYP1B1

The potential differences in overexpression between CYP1A1 and CYP1B1 in human tumors will be evaluated. Because CYP1A1 and CYP1B1 do not seem to be expressed in normal cells, these enzymes could become an important target in cancer therapy.