Essais cliniques

ClinicalTrials.gov

Vous trouverez ci-dessous une liste de tous les essais cliniques ouverts de phase III recensés par www.clinicaltrials.gov, un registre international d’essais cliniques soutenus par les gouvernements ou par des initiatives privées.
Vous pouvez rechercher dans cette liste en saisissant un type de cancer, en sélectionnant un pays ou en entrant un mot clé ou le code NCT de l’essai clinique. En combinant plusieurs options de recherche, vous pouvez affiner votre recherche.
Par exemple, si vous êtes une patiente française atteinte d’un cancer du sein, vous pouvez saisir “cancer du sein” comme type de cancer et recherchez des essais cliniques en France.
Pour un même essai clinique, vous pouvez regarder les différents centres, y compris dans un autre pays que le vôtre. Les essais cliniques que vous aurez sélectionnés sont mis en lien avec la page originale du site www.clinicaltrials.gov que vous devrez consulter afin d’avoir plus d’informations. Reliable Cancer Therapies liste chaque semaine les essais cliniques disponibles pour le traitement du cancer.
Cette partie du site Internet est uniquement disponible en anglais.

It is still not clear whether a positive AGO-score just selects patients with less aggressive biologic tumor behavior who as well would have had a positive outcome by chemotherapy only, or , if it is a score selecting patients who really benefit from surgery. Nevertheless, the AGO-score was confirmed to select patients with a less than 30% risk of ending with residual tumor after surgery for recurrent disease. This could avoid including patients into the present...
RATIONALE: Aspirin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. The use of aspirin may slow disease progression after surgery. It is not yet known whether aspirin is more effective than a placebo in treating colorectal cancer that has been completely removed by surgery. PURPOSE: This randomized phase III trial is studying aspirin to see how well it works compared with a placebo in treating patients with Dukes stage C...
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Measuring blood levels of tumor cells may help in learning how well chemotherapy works to kill metastatic breast cancer cells and allow doctors to plan better treatment. When blood levels of tumor cells are high while receiving chemotherapy, it is not yet known whether it is more effective to change...
RATIONALE: Drugs used in chemotherapy, such as paclitaxel and polyglutamate paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Paclitaxel and polyglutamate paclitaxel may also stop the growth of ovarian epithelial or peritoneal cancer by blocking blood flow to the tumor. Sometimes, after treatment, the tumor may not need additional treatment until it progresses. In this case,...
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, carboplatin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving them in different ways may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating patients with ovarian epithelial cancer, primary...
RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor...
RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. It is not yet known whether combination...
RATIONALE: Letrozole may prevent breast cancer in postmenopausal women with a BRCA1 or BRCA2 mutation. PURPOSE: This randomized phase III trial is studying letrozole to see how well it works compared with a placebo in preventing breast cancer in postmenopausal women with a BRCA1 or BRCA2 mutation.
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving them after surgery may kill any tumor cells remaining after surgery. It is not yet known whether docetaxel is more effective than ixabepilone when given after surgery and combination chemotherapy in treating breast cancer. PURPOSE: This...
RATIONALE: Estrogen can cause the growth of breast cancer cells. Letrozole may fight breast cancer by lowering the amount of estrogen the body makes. It is not yet known which regimen of letrozole is more effective in postmenopausal women who have received hormone therapy for early-stage breast cancer. PURPOSE: This randomized phase III trial is comparing two different regimens of letrozole in preventing cancer in postmenopausal women who have received 4-6 years...